{"id":106567,"date":"2021-06-30T09:00:42","date_gmt":"2021-06-30T07:00:42","guid":{"rendered":"https:\/\/ivi-fertility.com\/?p=106567"},"modified":"2022-04-12T17:35:14","modified_gmt":"2022-04-12T15:35:14","slug":"duostim-ovarian-stimulation","status":"publish","type":"post","link":"https:\/\/ivi-fertility.com\/blog\/duostim-ovarian-stimulation\/","title":{"rendered":"DuoStim ovarian stimulation : less time to obtain a healthy embryo"},"content":{"rendered":"

Once again, IVI wins the race against time, on this occasion using the DuoStim strategy. At the 37th<\/sup> annual ESHRE congress<\/strong><\/a> which this year for the second time, due to the health situation, is held on line, Dr Mar\u00eda Cerrillo, a gynaecologist with IVI Madrid, presented the work titled \u201cThe DuoStim strategy shortens the time to obtain an euploid embryo in poor prognosis patients: a non-inferiority randomized controlled trial\u201d.<\/p>\n

We work constantly to provide options to patients with severe prognoses, for whom reducing the time to obtain oocytes and embryos is key to having a healthy baby. The DuoStim protocol consists of performing two consecutive stimulations without waiting for menstruation. This technique is an alternative for poor responders who need to accumulate a large number of oocytes, and later embryos, in the shortest time possible, to perform a preimplantation genetic test. IVI is the first to compare DuoStim results with those of two conventional delayed stimulations. The main difference is the reduction of the time necessary to obtain a healthy embryo by nearly half.<\/p>\n

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Two groups of patients with ovarian stimulation for a healthy embryo<\/h2>\n

For this study IVI recruited 80 patients all over age 38 who, due to their characteristics, required a preimplantation genetic testing<\/a>. Two groups were established, one with DuoStim and another with two delayed stimulations.<\/p>\n

\u201cAlthough there have already been studies and data on performing two consecutive stimulations in certain patients, we are the first to conduct a comparison of two stimulations in the same cycle with two delayed stimulations. The DuoStim idea arose after verifying that oocytes obtained in phases other than the follicular phase are equally useful and viable. We concluded that patients stimulated by DuoStim were able to reduce by half the time necessary to obtain a healthy embryo for transfer, therefore making a reduction in the time to achieve pregnancy more likely\u201d, explains Dr Cerrillo.<\/p>\n

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Less time to obtain healthy embryos<\/h2>\n

\u201cUpon comparing the results of the two groups, it was determined that there was no variation in the days on which the two stimulations were performed, nor in the number of oocytes or healthy embryos obtained. The main difference was in the number of days that were necessary to obtain a healthy embryo. In the case of the patients stimulated with DuoStim, the time necessary to obtain a euploid embryo was 23.3 days versus 44.1 days in the control group, or group of patients stimulated by means of two conventional delayed stimulations\u201d, Dr Cerrillo says.<\/p>\n

Three common questions arise:<\/p>\n