{"id":106801,"date":"2021-07-16T14:59:24","date_gmt":"2021-07-16T12:59:24","guid":{"rendered":"https:\/\/ivi-fertility.com\/?p=106801"},"modified":"2022-04-12T17:35:14","modified_gmt":"2022-04-12T15:35:14","slug":"ivi-specialists-in-high-complexity-assisted-reproduction","status":"publish","type":"post","link":"https:\/\/ivi-fertility.com\/blog\/ivi-specialists-in-high-complexity-assisted-reproduction\/","title":{"rendered":"IVI: Specialists in High Complexity Assisted Reproduction"},"content":{"rendered":"<p>Motherhood is a desired and long-awaited moment for hundreds of women. But the reality is that for some it is a rocky road with obstacles along the way. Assisted reproduction is one of the most avant-garde fields of medicine, in which research and technology are at the service of our patients\u2019 dreams. For this reason, at IVI we are specialists in high complexity assisted reproduction. So we can treat even the most difficult cases and help them achieve what they long for.<\/p>\n<p>&nbsp;<\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_68_1 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title \" >Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ivi-fertility.com\/blog\/ivi-specialists-in-high-complexity-assisted-reproduction\/#Implantation_failure_or_repeat_miscarriages\" title=\"Implantation failure or repeat miscarriages\">Implantation failure or repeat miscarriages<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ivi-fertility.com\/blog\/ivi-specialists-in-high-complexity-assisted-reproduction\/#Diagnostic_study_for_implantation_failures_or_repeated_miscarriages\" title=\"Diagnostic study for implantation failures or repeated miscarriages\">Diagnostic study for implantation failures or repeated miscarriages<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ivi-fertility.com\/blog\/ivi-specialists-in-high-complexity-assisted-reproduction\/#Therapeutic_study_for_implantation_failures_or_repeated_miscarriages\" title=\"Therapeutic study for implantation failures or repeated miscarriages\">Therapeutic study for implantation failures or repeated miscarriages<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ivi-fertility.com\/blog\/ivi-specialists-in-high-complexity-assisted-reproduction\/#Becoming_a_mother_after_40\" title=\"Becoming a mother after 40\">Becoming a mother after 40<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ivi-fertility.com\/blog\/ivi-specialists-in-high-complexity-assisted-reproduction\/#Patients_with_low_ovarian_reserve\" title=\"Patients with low ovarian reserve\">Patients with low ovarian reserve<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ivi-fertility.com\/blog\/ivi-specialists-in-high-complexity-assisted-reproduction\/#i\" title=\"\u00a0\">\u00a0<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/ivi-fertility.com\/blog\/ivi-specialists-in-high-complexity-assisted-reproduction\/#IVI_Regenerate_Ovary\" title=\"IVI Regenerate Ovary\">IVI Regenerate Ovary<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Implantation_failure_or_repeat_miscarriages\"><\/span><strong>Implantation failure or repeat miscarriages<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Implantation failure is when the patient is not able to become pregnant after the transfer of 2 euploid embryos. This type of embryos are chromosomally normal embryos \u2013containing 46 chromosomes. Implantation failure can also occur in cases where pregnancy is also not achieved when 4 blastocysts have been transferred. Unfortunately, 5% of IVI patients have experienced this at some time.<\/p>\n<p>On the other hand, <strong>repeat miscarriage<\/strong> is diagnosed when a woman has had two gestational losses before the 24th week. In this case, 6% of our patients have experienced two or more previous miscarriages.<\/p>\n<p>If you are in either of these two situations, at IVI we are specialists in<strong>\u00a0High Complexity Assisted Reproduction<\/strong>\u00a0and we can help you. We have a study that approaches the issue from two angles: the diagnostic study \u2013analysing personal and family history\u2013 and the therapeutic study \u2013through a series of tests.<\/p>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Diagnostic_study_for_implantation_failures_or_repeated_miscarriages\"><\/span><strong>Diagnostic study for implantation failures or repeated miscarriages<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ul>\n<li>Imaging tests \u20133D ultrasound, hysteroscopy or laparoscopy\u2013 to detect possible genital organic pathologies.<\/li>\n<li>Blood tests to determine causes associated with maternal thrombophilias.<\/li>\n<li>Endometrial receptivity analysis<\/li>\n<li><a href=\"https:\/\/ivi-fertility.com\/assisted-reproduction-treatments\/pgd-pgt\/\">Preimplantation Genetic Testing\u00a0<\/a>(PGT-A) for the detection of chromosomal abnormalities<\/li>\n<\/ul>\n<p>In the event that this series of tests does not enable our specialists to determine the cause of either of these two problems, a reproductive immunology study will be considered in our\u00a0Immunology Unit. There are occasions in which these infertility problems, which seem to have no apparent reason, are due to immunological alterations.<\/p>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Therapeutic_study_for_implantation_failures_or_repeated_miscarriages\"><\/span><strong>Therapeutic study for implantation failures or repeated miscarriages<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ul>\n<li>Imaging tests \u20133D ultrasound, hysteroscopy or laparoscopy\u2013 for the treatment of possible genital organic pathologies detected.<\/li>\n<li>Treatment, guided by haematologists specialising in reproductive pathology, against congenital or acquired thrombophilias.<\/li>\n<li>Preimplantation Genetic Testing (PGT-A + PGT-SR) or gamete donation, to prevent the transmission of parental chromosomal anomalies or embryonic anomalies, in coordination with specialists from IVI\u2019s Reproductive Genetics Unit.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Becoming_a_mother_after_40\"><\/span><strong>Becoming a mother after 40<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Many women decide to postpone motherhood \u2013for whatever reason\u2013 and when they decide it is the right time, they encounter many difficulties. Age is one of the main obstacles when a woman undergoes assisted reproduction treatment. From the age of 35 onwards, there is a decrease in the quality of the oocytes. This increases the chances of generating embryos with aneuploidies. Age also affects the number of oocytes, which can lead to a low ovarian reserve. If this happens, after <strong>ovarian stimulation for an IVF cycle<\/strong>, the patient does not generate enough oocytes.<\/p>\n<p>In cases where a woman wants to become a mother after the age of 40, the first thing to do is to carry out a fertility study. For this purpose we have different diagnostic tests, such as 3D ultrasound and <a href=\"https:\/\/ivi-fertility.com\/blog\/anti-mullerian-hormone-amh\/\">anti-M\u00fcllerian hormone (AMH)<\/a> testing. The second step will be for the specialist and the patient to make a joint decision. Finally, based on the most suitable treatment chosen, we offer patients different options adapted to their case.<\/p>\n<p>Preimplantation Genetic Testing (PGT-A) to select the best embryos, with the aim of achieving a healthy baby in the shortest possible time.<\/p>\n<ul>\n<li><strong>Oocyte accumulation<\/strong>, for those cases in which there is a low ovarian reserve and PGT-A has been previously recommended. It may also be advisable for these patients to opt for DuoStim.<\/li>\n<li><strong>Egg donation<\/strong>, to rule out the negative impact of age on oocyte quality.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Patients_with_low_ovarian_reserve\"><\/span><strong>Patients with low ovarian reserve<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>A woman is considered to be a low responder when optimal ovarian stimulation is not achieved. The main characteristic of these cases is the low number of oocytes. Therefore, the lower the number of oocytes, the fewer embryos to select and transfer. As a result, the chances of achieving pregnancy in this type of patient are lower. As we mentioned above, childbearing age is getting later and later, so in the future there will be more women with a low response. This may be a new challenge for IVI in High Complexity Assisted Reproduction.\u00a0Fortunately, however, there are several options available to us:<\/p>\n<ul>\n<li><strong>Accumulation of oocytes<\/strong> from different cycles. This way we manage to combine the possible transfers into a single transfer. This technique achieves lower cancellation rates, higher cumulative newborn rate and cycles with a higher number of frozen embryos.<\/li>\n<li><strong>Genetic PLUS IVF<\/strong>, as the main factor in low response rates is the decrease in ovarian reserve due to age. Although there may also be other causes, which lead to low response and a higher probability of generating aneuploid oocytes. In cases of low responders with advanced maternal age, oocyte accumulation is the best option. This, together with PGT-A helps to rule out chromosomally abnormal embryos.<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"i\"><\/span>\u00a0<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h2><span class=\"ez-toc-section\" id=\"IVI_Regenerate_Ovary\"><\/span>IVI Regenerate Ovary<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>In addition, at IVI we are working to offer you the <strong>IVI Regenerate\u00a0Ovary<\/strong> technique in the near future. This involves the application of plasma rich in growth factors (PRGF). It is a promising alternative for patients diagnosed with low ovarian reserve, among other issues. This is another example of IVI&#8217;s expertise in high complexity assisted reproduction<\/p>\n<p>One of the maxims of IVI and its professionals, throughout its 30 years of history, is constant research and innovation. The fact is that many of the patients who come to our clinics have a difficult history, for different reasons. For them, we are specialists in high complexity assisted reproduction. In order to provide them with solutions.<\/p>\n","protected":false},"excerpt":{"rendered":"Motherhood is a desired and long-awaited moment for hundreds of women. But the reality is that for some it is a rocky road with obstacles along the way. Assisted reproduction is one of the most avant-garde fields of medicine, in which research and technology are at the service of our patients\u2019 dreams. For this reason,&#8230; <a class=\"view-article\" href=\"https:\/\/ivi-fertility.com\/blog\/ivi-specialists-in-high-complexity-assisted-reproduction\/\">View Article<\/a>","protected":false},"author":34,"featured_media":106802,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[17],"tags":[170,64],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>IVI fertility clinics: Specialists in High Complexity Assisted Reproduction<\/title>\n<meta name=\"description\" content=\"At IVI we are specialists in high complexity assisted reproduction, so that we can treat even the most difficult cases and help them.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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