{"id":46504,"date":"2024-01-25T10:53:16","date_gmt":"2024-01-25T08:53:16","guid":{"rendered":"https:\/\/ivi-fertility.com\/?p=46504"},"modified":"2024-01-31T16:35:39","modified_gmt":"2024-01-31T14:35:39","slug":"low-amh-levels-fertility","status":"publish","type":"post","link":"https:\/\/ivi-fertility.com\/blog\/low-amh-levels-fertility\/","title":{"rendered":"Low AMH Levels: understanding the impact on fertility"},"content":{"rendered":"

Low AMH levels are generally considered to be an indicator of a low ovarian reserve<\/strong>. It is quite normal for a woman\u2019s AMH levels to decline as she gets older. In younger women this may be a sign of premature loss of fertility. Low AMH fertility treatment could consist of IVF together with hormone treatment.<\/p>\n

High AMH levels for IVF are anything within the range of normal for a woman under 38. However, looking at what are the AMH levels in an individual is only part of the diagnostic process.<\/p>\n

\"amh\"<\/p>\n

What is Anti-M\u00fcllerian Hormone (AMH)?<\/strong><\/h2>\n

AMH refers to the Anti-Mullerian Hormone<\/a>. This hormone is secreted by the granulosa cells surrounding the developing egg cells in the ovary. AMH levels provide information about your ovarian reserve<\/strong>, which is the quantity of egg cells remaining in your ovaries.<\/p>\n

Therefore, a low level is considered to be a sign of a low ovarian reserve, i.e. few remaining follicles. This would be normal for a woman who is approaching menopause. Conversely, a woman who has polycystic ovarian syndrome, characterised by the presence of many small ovarian follicles, would normally be expected to show high levels of AMH<\/strong>.<\/p>\n

How AMH impacts fertility\u00a0<\/strong><\/h2>\n

As we have explained, high AMH levels indicate a higher quantity of oocytes, and vice versa. If these levels show diminished ovarian reserve, fertility may be at risk,<\/a> and there is even a possibility of early menopause.<\/p>\n

It is important to note that AMH is just one contributing factor to fertility<\/strong>. Other factors such as age and the cause of low Anti Mullerian hormone levels also play a role. Next, we will examine some effects resulting from low levels of this hormone.<\/p>\n

Reduced egg quantity and quality<\/h3>\n

The decrease in ovarian reserve due to age is often accompanied by a lower quality of oocytes. Therefore, AMH indicates not only a reduced quantity of oocytes but also a higher likelihood of aneuploidy<\/strong> (chromosomic abnormalities).<\/p>\n

Increased risk of miscarriage<\/h3>\n

Low anti mullerian hormone levels also entail an increased risk of miscarriage, although specialists emphasize the need to consider other factors as well. For instance, the risk may escalate if low AMH coincides with advanced maternal age<\/strong>.<\/p>\n

Challenges in conception<\/h3>\n

The significance of AMH levels in the quest for pregnancy will depend on its origin. For instance, if the decline in levels is due to conditions such as polycystic ovary syndrome (PCOS), an appropriate treatment may increase AMH levels<\/strong>.<\/p>\n

What AMH test results tells<\/strong><\/h2>\n

Typically, AMH normal range of values range between 1 and 4 ng\/ml<\/strong>. The assessment of ovarian reserve based on recorded parameters would be as follows:<\/p>\n\n\n\n\n\n
2 \u2013 1 ng\/ml<\/td>\nLow ovarian reserve<\/td>\n<\/tr>\n
1 \u2013 3 ng\/ml<\/td>\nNormal ovarian reserve<\/td>\n<\/tr>\n
3 ng\/ml<\/td>\nHigh ovarian reserve<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

However, it is crucial to consider the woman’s age when interpreting blood hormone results<\/strong>. The following are reference AMH values based on age:<\/p>\n\n\n\n\n\n\n
Under 33 years<\/td>\n2.1 ng\/ml<\/td>\n<\/tr>\n
Between 33 and 37 years<\/td>\n1.7 ng\/ml<\/td>\n<\/tr>\n
Between 38 and 40 years<\/td>\n1.1 ng\/ml<\/td>\n<\/tr>\n
41 years and older<\/td>\n0.5 ng\/ml<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

It is important to note, as mentioned earlier, that AMH levels do not always correlate with age. Therefore, to make a comprehensive assessment of female fertility, additional tests will also be conducted<\/strong>. Follicle count, as well as tests for FSH, estradiol, or prolactin, are among them.<\/p>\n

These measurements can also be used to help predict the response to fertility treatments such as in vitro fertilization.<\/p>\n

Causes of Low AMH Levels<\/strong><\/h2>\n

In general, there is no single answer to determine the origin of low anti-mullerian hormone levels<\/strong>. Below, we list some possible causes:<\/p>\n

Age<\/h3>\n

As mentioned before, age is the most common cause of low anti mullerian hormone levels<\/strong>, as well as diminished ovarian reserve.<\/p>\n

Pathologies: PCOS, endometriosis<\/h3>\n

PCOS or endometriosis can lead to high AMH levels, causing fertility problems.<\/p>\n

Premature ovarian failure (POF)<\/h3>\n

Premature Ovarian Failure (POF) involves the cessation of ovarian activity in women younger than 40<\/strong>, and this can result in low AMH levels and infertility.<\/p>\n

Oncological therapies, environmental factors<\/h3>\n

Chemotherapy, radiation or exposure to environmental toxins can have an impact on reproductive capacity and AMH levels.<\/p>\n

Autoimmune diseases<\/h3>\n

Lupus or rheumatoid arthritis can inflame or damage the ovaries, leading to a decrease in AMH levels.<\/p>\n

Treatment Options for Low AMH<\/strong><\/h2>\n

For many women, a declining level of fertility and failure to conceive is the trigger to consult for advice<\/strong>. Providing your clinical consultant at IVI considers there is an AMH normal range level for IVF, in vitro fertilisation could well be the treatment recommended. If on the other hand the AMH levels and thus the ovarian reserve are so low that this form of intervention is unlikely to succeed, your clinician may advise you to consider the use of egg donation.<\/p>\n

In vitro fertilization (IVF)<\/h3>\n

The process is relatively straightforward. These are the different steps of IVF:<\/p>\n