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20 June 2025

Does Folic Acid Boost Fertility?

folic acid for fertility
Home Blog Does Folic Acid Boost Fertility?
By the Editorial Committee IVI Blog

Folic acid is an essential vitamin that plays a key role in overall health, especially for women trying to conceive. While it’s most commonly known for helping prevent neural tube defects during pregnancy, many wonder: Can folic acid actually increase fertility?

In this article, we’ll explore the connection between folic acid and fertility, how it supports conception, and why it’s so important for reproductive health.

Table of Contents

Toggle
  • What is folic acid?
  • Folic acid and female fertility
    • Improves egg quality
    • Supports a regular menstrual cycle
    • Promotes hormonal balance
    • Reduces the risk of miscarriage
    • Enhances fertility treatment outcomes
  • Folic acid and male fertility
  • How Much Folic Acid Do You Need to Support Fertility?

What is folic acid?

Folic acid is the synthetic form of vitamin B9, one of the B-complex vitamins found in both food and supplements. The name “folic” comes from the Latin word “folium”, meaning “leaf,” since it’s naturally present in leafy greens like spinach, Swiss chard, and broccoli.

Folic acid is vital for red blood cell production, DNA development, and proper cell function. During pregnancy, it’s especially crucial for preventing neural tube defects such as spina bifida and anencephaly. But its role goes beyond pregnancy — it’s also essential for overall health and female fertility.

Folic acid and female fertility

Folic acid is one of the most frequently recommended vitamins for women trying to get pregnant. Several studies suggest it can have a positive impact on fertility. Here’s how it may support your chances of conceiving:

Improves egg quality

One of the most studied effects of folic acid on female fertility is its influence on egg quality. Vitamin B9 plays a key role in DNA synthesis and cell division, both of which are essential during egg maturation. Low folic acid levels can negatively affect egg health, potentially disrupting ovulation or fertilization.

Research shows that women with sufficient folic acid levels tend to have more healthy eggs and better egg quality compared to those with a deficiency. When folic acid levels are low, ovulation may be irregular or impaired, making conception more difficult.

Supports a regular menstrual cycle

Folic acid also helps regulate the menstrual cycle—an important factor for fertility. A regular cycle increases the likelihood of ovulating at the optimal time, making it easier to plan for pregnancy.

Studies have shown that women with healthy folic acid levels are more likely to experience consistent menstrual cycles, improving their chances of conception.

Promotes hormonal balance

Folic acid supports the production and regulation of reproductive hormones, including estrogen and progesterone. These hormones are essential for ovulation, embryo implantation, and early pregnancy maintenance.

When folic acid is lacking, hormonal imbalances can occur, which may interfere with fertility. Ensuring adequate levels of this vitamin can help optimize hormone function and support reproductive health.

Reduces the risk of miscarriage

Some studies suggest that folic acid supplementation may help lower the risk of miscarriage. A European study found that women who took folic acid supplements before and during early pregnancy had a lower risk of miscarriage compared to those who didn’t.

This may be due in part to folic acid’s ability to lower homocysteine levels—an amino acid that, when elevated, has been linked to pregnancy complications including miscarriage.

Enhances fertility treatment outcomes

For women undergoing fertility treatments such as IVF, folic acid can be especially beneficial. Some studies have found that women taking folic acid supplements during fertility treatment were more likely to conceive than those who did not. Folic acid may also improve ovarian response to gonadotropins and increase embryo quality, making it a valuable supplement during assisted reproduction.

Folic acid and male fertility

Although most research on folic acid and fertility has focused on women, some studies suggest it may also support male reproductive health.

Vitamin B9 is involved in sperm production and overall cell function in men.

Men with adequate folic acid levels tend to have higher sperm counts and better sperm quality compared to those who show deficient levels.

Additionally, folic acid deficiency in men may increase the risk of chromosomal abnormalities in sperm, which could impact embryo development.

While more research is needed, the evidence so far suggests that folic acid may play a beneficial role for men trying to conceive.

How Much Folic Acid Do You Need to Support Fertility?

Women trying to conceive are encouraged to start taking a folic acid supplement even before getting pregnant. The recommended daily dose for most women is 400 micrograms (mcg).

This amount is generally enough to support reproductive health and reduce the risk of neural tube defects if pregnancy occurs.

It’s important to understand that folic acid isn’t a cure-all for infertility. While it can be highly beneficial, fertility is influenced by many factors including lifestyle, age, medical conditions, and sexual habits. Always consult a physician or fertility specialist to determine the right dosage and supplements for your specific needs.

In summary, folic acid plays a vital role in both female and male fertility. This essential vitamin doesn’t just support prenatal health — it also helps improve egg quality, regulate menstrual cycles, balance reproductive hormones, and reduce the risk of miscarriage. For women trying to conceive, taking a folic acid supplement can be a smart and proactive step toward optimizing fertility.

While folic acid may not solve every fertility challenge by itself, its benefits for conception and early pregnancy are significant enough to make it a key part of preconception care. We always point out that speaking with a healthcare provider is the best way to receive personalized guidance and improve your journey to fertility.

If you’d like to schedule a consultation at IVI or get more information with no obligation, simply fill out the contact form below.

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