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Egg donation

Egg donation is the process whereby a woman uses oocytes from a donor to fulfil her desire of becoming a mother. The oocytes from the donor will be combined with spermatozoa from the recipient couple to produce embryos; these will be transferred to the recipient in order to achieve the longed-for pregnancy. As such, oocytes donation makes the miracle of life possible for women who would not be able to have children any other way.

Egg donation

Recommended in the case of:

  • Older women.
  • Women with ovarian failure due to menopause, premature ovarian failure or ovarian surgery.
  • Women who cannot use their own oocytes, due to poor quality or because of hereditary diseases that cannot be detected by PGD techniques; women who have repeatedly failed to get pregnant through in vitro fertilisation.
  • Women whose ovaries are inaccessible for obtaining oocytes.
  • Repeated miscarriages.
  • Chromosomal abnormalities in the woman or her embryos.

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  • Primary ovarian failure is when menstruation does not begin during puberty (gonadal dysgenesis – Turner syndrome, Swyer syndrome, pure gonadal dysgenesis – Savage syndrome or resistant ovary syndrome).
  • Premature ovarian failure is when a loss of ovarian function is experienced before the age of 40, with periods starting to become irregular and eventually stopping altogether. Some of the causes of this include:
    1. Hereditary factors: carriers of Fragile X Syndrome, etc.
    2. Enzyme alterations: galactosemia, 17a-hydroxylase deficiency. Gonadotropin secretion defect.
    3. Autoimmune disorders: MEN, or multiple endocrine neoplasia syndrome, Addison’s syndrome, diabetes mellitus, hypothyroidism, anti-ovarian antibodies, etc.
    4. Infectious factors: parotiditis, rubella.
    5. Environmental factors: smoking, etc.
    6. Surgical castration: due to cysts or tumours on the ovaries.
    7. Past treatment with chemotherapy or radiotherapy.
  • Repeated failure with IVF is when women do not respond to ovarian stimulation, or when they fail to achieve fertilisation on several occasions with ICSI, or when they experience repeated embryo implantation failure.

Recommended in the case of:

  • Men who have no spermatozoa.
  • Men who are carriers of a genetic disease which cannot be studied in the embryos, or who are carriers of a sexually transmitted disease.
  • Chromosomal abnormalities in the semen.
  • Women who do not have a male partner.


90% of patients who undergo an assisted reproduction treatment at IVI become pregnant.


IVI is a pioneer in the latest assisted reproduction technology in order to present the best results.


97% of our patients recommend IVI.
IVI provides personalised care and support during all stages of treatment.


We are not the most expensive choice. We offer the most treatment options in order to achieve the best results.

Egg donation

Egg Donors

Oocytes donation was legalised by Spanish legislation in 1988 (Law 35/1988, of 22 November). Donors must fulfil a series of requirements in order to donate their eggs:

  • Age: 18 to 35.
  • Their genetic history must comply with the requirements of the legislation currently in force.
  • They must have a normal reproductive system.

In order to be accepted into the oocyte donation programme at IVI, women must undergo a full medical and psychological assessment that provides us with valuable information about their fertility, their state of health and their potential to become mothers. They are given a very thorough gynaecological check-up which will rule out the presence of cysts, myomas, polyps and other irregularities of the reproductive organs. A chromosomal study will also be carried out to rule out the possibility of any future defects in her own babies or in babies born to recipients of her oocytes. It will be confirmed that she is free from any transmissible diseases such as HIV, hepatitis and syphilis, and her blood group and Rh factor will also be checked.

According to the law on assisted reproduction techniques, oocyte donation is anonymous and voluntary, and as such IVI does not reveal the identity of either donors or recipients. However, information which is important for monitoring the pregnancy correctly can be provided, such as the blood group and age of the donor.


The woman receiving the embryos must undergo treatment to prepare her endometrium prior to embryo transfer.

Egg donation

Pharmacological treatment

Recipient women are given medication to prepare their uterus for implantation by the transferred embryos. While they are waiting for a donation, they must keep in close contact with their IVI centre so that they can be located.

As soon as there is a suitable donation for the particular case in question, the patients will be informed with sufficient advance warning for proceeding to fertilisation of the oocytes.

Egg donation

Preparation of the semen

The semen can be obtained on the same day as the oocyte donation, following a period of sexual abstinence. It is prepared in the laboratory in order to remove certain components and to select the most suitable spermatozoa for fertilising the donated oocyte. Semen can also be cryopreserved in advance of donation, and on the day when there is a compatible oocyte donor the previously frozen sample can be used.

Egg donation

Fertilisation and transfer

The spermatozoa and oocytes are brought into contact through the technique of in vitro fertilisation or sperm microinjection. Once the embryos have been fertilised, they stay in the in vitro fertilisation laboratory until it is time for them to be transferred. Once fertilisation has been achieved, the number of embryos to be transferred into the woman’s uterus is selected. The perfect moment for this transfer, as well as the number of embryos to be transferred, will be decided by the doctors based on the medical history of the couple, the number of embryos obtained and their characteristics, and the individual circumstances of the present treatment cycle.


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