phoneFree call from UK 0800 52 00 161 / Other countries: +34 960 451 185 personPrivate Area
phone

Free call

Request information
IVI IVI
MENUMENU
  • Treatments and services
        • ASSISTED REPRODUCTION
          • Artificial Insemination (AI)
          • In Vitro Fertilisation (IVF)
          • Egg donation
          • Genetic IVF (IVF + PGT-A)
        • PRESERVATION OF FERTILITY
          • Preservation of Fertility
        • IVI BABY PLAN
          • IVI Baby
        • TECHNIQUES
          • Vitrification of oocytes
          • EmbryoScope®
          • Semen Donation
          • ICSI
          • MACS
          • ROPA Method
          • Perfect Match 360º
        • TEST
          • Preimplantation Genetic Testing (PGT)
          • Non-Invasive Prenatal Tests
          • CGT: Compatibility Genetic Test
        • OUR DONORS
          • IVI: one of the world’s largest egg banks
        • Success rates
        • Prices
        • True Stories
        • The team
  • Clinics
        • Spain
          • A Coruña
          • Alicante
          • Almeria
          • Barcelona
          • Bilbao
          • Burgos
          • Cartagena
          • Castellon
          • Girona
          • Ibiza
          • Las Palmas
          • Lleida
          • Madrid – Alcorcón
          • Madrid – Aravaca
          • Málaga
          • Mallorca - Manacor
          • Mallorca - Palma
          • Murcia
          • Pamplona
          • Salamanca
          • San Sebastián
          • Santander
          • Sevilla
          • Tenerife
          • Valencia
          • Valladolid
          • Vigo
          • Vitoria
          • Zaragoza
        • United Kingdom
          • London
        • Portugal
          • Faro
          • Lisboa
        • Italy
          • Milano
          • Roma Casilino
          • Roma Parioli
        • Argentine
          • Buenos Aires
        • Panama
          • Panamá
        • Chile
          • Santiago de Chile
        • Brazil
          • Salvador
        • USA
          • RMA of Florida
          • RMA of New Jersey
          • RMA of Philadelphia
          • RMA of Southern California
  • FAQs
        • Your first visit to IVI
        • How hormones affect your ability to get pregnant
        • What is infertility?
        • Causes of infertility
        • IVI around the world
        • Where Life Begins
        • Quality and continuous improvement
        • COD-19
        • Coronavirus: COVID-19
  • Egg Donation Program in Spain
  • Blog
  • Request information
  • Submenu-item-responsive-2
    • Egg Donation Program in Spain
    • Blog
    • Private area
  • Submenu-item-responsive-3
    • Success rates
    • Prices
    • The team
    • True stories

24 October 2014

Women’s excessweight can negatively impact ivf success rate through an anormal embryo metabolism

Home > Press room > Women’s excessweight can negatively impact ivf success rate through an anormal embryo metabolism
Women’s excessweight can negatively impact ivf success rate through an anormal embryo metabolism

A study conducted by IVI Fertility Clinic has found that embryos of obese women work differently compared to those of normal weight
A recent study undertaken by the world’s largest multi-centre fertility clinic, IVI, has concluded that low IVF success rates in obese women may be, at least partly, a consequence of an abnormal embryo metabolism, that is different in embryos of normal weight women.
The study carried out by Associate Professor Doctor JoséBellver at IVI Fertility sought to determine whether the metabolomic profile in the spent culture media*of day three embryos is different in obese and normal weight women undergoing IVF treatment. The study also considered the impact of Polycystic Ovary Syndrome (PCOS) which can worsen the metabolic situation of obesity.
Twenty-eight women, all aged below thirty-eight years old with normal uterus and ovaries, were put into three groups:obese non-PCOS, obese with PCOS and normal weight, and all women underwent their first IVF attempt.
To determine the differences inembryo function, researchers took samples from the secreted spent media culture of 56 day three embryos.Blood tests were also taken from the women providing an overall picture of their body’s chemical balance and metabolism.
The preliminary results found the metabolites detected in the spent culture media of the day three embryos were different in normal weight and obese women. This means the embryos in obese women work differently by consuming and releasing different metabolites from and to the culture media.
The study concludes that there seems to be a difference in the embryo metabolism depending on female body mass index, perhaps related to the reduced implantation and ongoing pregnancy rates described in obese women. Embryo metabolism was not affected by the presence of PCOS, although the sample size was too limited in this group of patients to obtain definitive conclusions.
IVI Fertility Associate Professor Dr José Bellver comments:
“Our study has shown that embryos work in a different way according to the female body mass index. In a recent analysis we have identified some of these different metabolites. It seems that embryos from obese women secrete fewer quantities of saturated fatty acids to the culture media than embryos from normal weight women.
Our findings may be related to the lower success rates of implantation and ongoing pregnancy observed in obese women. These findings open a new line of research for us.”
Further details of the study were presented at the annual meeting of the American Society for Reproductive Medicine 2014.

Share on social networks

twitter facebook

Share on social networks

twitter facebook

PRESS ROOM CONTACTS

  • Lucía Renau
  • Dori Argente
  • Email: prensa@ivi.es
  • Phone number: (0034) 96 317 36 10
  • Calle Colón, 1 - 46004 (Valencia)

PRESS PACK

Last update
February 2020

Download PDF

Back to toparrow_drop_up
IVI

© 2021 IVI.
All rights reserved

  • Legal Notice
  • Cookies Policy
  • Assisted reproduction treatments
  • Clinics
  • FAQs
  • Corporate information
  • IVI Global Education
  • IVIRMA Innovation
  • Jobs at IVI
  • Press room
  • IVIRMA Media Awards
HEAD OFFICES
  • location_on Calle Colón 1, 4ª planta, 46004 Valencia. España.
  • España
  • Italia
  • Portugal
  • France
  • Deutschland
  • РОССИЯ
  • UK
COUNTRY
International
España Italia Portugal France Deutschland РОССИЯ UK
  • Certificado
  • Certificado
  • Certificado
  • logo
SOCIAL NETWORKS
    • rrss
    • rrss
    • rrss
    • rrss
    • rrss
RECEIVE OUR NEWSLETTER
Sending
Thank you for subscribing!